Cholesterol is important to our body but it should be
at normal levels. If the level is too high, it becomes danger that puts us at
very high risk of heart attack. The main functions of cholesterol are as part
of making cell walls, producing vitamin D and making certain hormones.
Low density lipoprotein (LDL) is known as bad
cholesterol while high density lipoprotein (HDL) is known as good cholesterol.
The cholesterols are carried by these two types of lipoprotein. The high level
of LDL can cause damaging to blood vessels because of its tendency to
infiltrate and accumulate within arterial walls. The elevated LDL also can
cause structural modification including oxidation and glycosylation. This can
lead to the development of atherosclerosis. The HDL can give benefits to human
hearts. It protects against coronary heart disease (CHD). It removes excess
cholesterol in the arterial wall and protects LDL against oxidation.
In 1963, it was the first reported of oats with its
properties of hypocholesterolemic or lowering the cholesterol level. In one
study, oats have shown its ability to lowering total cholesterol and LDL by 2
to 23% after ingesting 35-120g of oats per day. The oats include oat bran,
oatmeal and oat gum. Oats do not reduce cholesterol by displacing fat and
cholesterol intake and it was shown to reduce cholesterol levels when low fat
diet is consumed. In several studies, oats improves lipid profile by decreasing
LDL, increasing HDL as well as apolipoprotein.
The recommended intake of beta-glucan oats is 3g per
day for its effectiveness of cholesterol lowering effect. In one meta-analysis,
3 servings of 28g of oatmeal per day which provide 3g of beta-glucan daily, and
the result showed reduction of total cholesterol by an average 6mg/dL. 1%
reduction of cholesterol in blood reduces 2-4% risk of CHD. Thus, beta-glucan
is a major component of oats for cholesterol lowering effect.
In other cholesterol lowering mechanism, oats will
form to viscous gel by oat soluble fiber. Then, the formation will bind to bile
acids and increases their excretion within feces. More bile acids production can
reduce more blood cholesterol. In other mechanism, bacterial fermentation of
beta-glucan increases the release of short chain fatty acids which may inhibit
cholesterol biosynthesis. Soluble fiber also delay gastric emptying and reduce
postprandial insulin concentration which also inhibits cholesterol
biosynthesis. Oat soluble fiber also may reduce the intestinal absorption of
cholesterol.
Reference:
Katz, D. (2001). A scientific review
of the health benefits of oats. The Quaker Oats Com, 1–11. Retrieved
from http://roscomoss.com/pdf/HealthBenefitsofOats.pdf
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